Cytisine for vaping
A proposed independent study of cytisine, a plant-based compound already used in some countries to help smokers quit, in people who only vape.
ProposalScopingDesignFundedTestingData open
- Nicotine
- 20.0 mg
- wght
- 900
- wdth
- 50
Quitting vaping shouldn't be this hard.
Exhale is a new, open research network for better ways to quit nicotine vapes. The plan: people who vape, clinicians and researchers decide together which studies get funded, every result is published openly, and contributors earn EXHALE.
$EXHALE
Contract not deployed yet. The official address is published here at launch.
The step-down, the way the study would run it
20mg
Your usual strength, logged every day.
12mg
The first step down, with cravings tracked.
6mg
Half again. A slip is data, not failure.
3mg
The last step before zero.
0mg
Nicotine-free. The registry keeps counting.
A proposed schedule for the Nicotine step-down pods study, which has not started. It is not medical advice.
Why this matters
1.63M
US middle and high school students currently use e-cigarettes.
Source: CDC National Youth Tobacco Survey, 202426.3%
of those students vape every day.
Source: CDC National Youth Tobacco Survey, 20246.5%
of US adults currently use e-cigarettes, up from 4.5% in 2019.
Source: CDC National Health Interview Survey, 2023Millions want to stop. The tools were built for cigarettes.
Most quit programs and medicines were designed for smokers, not for the constant, all-day nicotine of a vape. Exhale pools community funding into research made for people who vape, keeps the data open, and lets the people trying to quit decide what gets studied next.
What the community could fund first
Nicotine step-down pods
A proposed structured taper that lowers nicotine strength week by week, measuring cravings and relapse along the way.
ProposalScopingDesignFundedTestingData open
Craving signals from wearables
A proposed test of whether heart rate and sleep data can warn someone of a craving early enough to act on it.
ProposalScopingDesignFundedTestingData open
Open quit-attempt registry
A planned registry of anonymised member quit attempts, methods and outcomes, to be published for any lab to analyse.
ProposalScopingDesignFundedTestingData open
Every quit attempt teaches us something.
Exhale is pre-launch. Follow along, and help decide which study comes first.